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Structural basis for S-adenosylmethionine binding and methyltransferase activity by mitochondrial transcription factor B1

Eukaryotic transcription factor B (TFB) proteins are homologous to KsgA/Dim1 ribosomal RNA (rRNA) methyltransferases. The mammalian TFB1, mitochondrial (TFB1M) factor is an essential protein necessary for mitochondrial gene expression. TFB1M mediates an rRNA modification in the small ribosomal subun...

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Detalles Bibliográficos
Autores principales:	Guja, Kip E., Venkataraman, Krithika, Yakubovskaya, Elena, Shi, Hui, Mejia, Edison, Hambardjieva, Elena, Karzai, A. Wali, Garcia-Diaz, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763538/ https://www.ncbi.nlm.nih.gov/pubmed/23804760 http://dx.doi.org/10.1093/nar/gkt547

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