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DNA double-strand–break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice
Although the DNA double-strand break (DSB) is defined as a rupture in the double-stranded DNA molecule that can occur without chemical modification in any of the constituent building blocks, it is recognized that this form is restricted to enzyme-induced DSBs. DSBs generated by physical or chemical...
Autores principales: | Schipler, Agnes, Iliakis, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763544/ https://www.ncbi.nlm.nih.gov/pubmed/23804754 http://dx.doi.org/10.1093/nar/gkt556 |
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