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Structural insight into negative DNA supercoiling by DNA gyrase, a bacterial type 2A DNA topoisomerase

Type 2A DNA topoisomerases (Topo2A) remodel DNA topology during replication, transcription and chromosome segregation. These multisubunit enzymes catalyze the transport of a double-stranded DNA through a transient break formed in another duplex. The bacterial DNA gyrase, a target for broad-spectrum...

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Detalles Bibliográficos
Autores principales:	Papillon, Julie, Ménétret, Jean-François, Batisse, Claire, Hélye, Reynald, Schultz, Patrick, Potier, Noëlle, Lamour, Valérie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763546/ https://www.ncbi.nlm.nih.gov/pubmed/23804759 http://dx.doi.org/10.1093/nar/gkt560

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