The eIF2α/ATF4 pathway is essential for stress-induced autophagy gene expression

In response to different environmental stresses, eIF2α phosphorylation represses global translation coincident with preferential translation of ATF4, a master regulator controlling the transcription of key genes essential for adaptative functions. Here, we establish that the eIF2α/ATF4 pathway direc...

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Detalles Bibliográficos
Autores principales: B’chir, Wafa, Maurin, Anne-Catherine, Carraro, Valérie, Averous, Julien, Jousse, Céline, Muranishi, Yuki, Parry, Laurent, Stepien, Georges, Fafournoux, Pierre, Bruhat, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763548/
https://www.ncbi.nlm.nih.gov/pubmed/23804767
http://dx.doi.org/10.1093/nar/gkt563

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