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Molecular mechanism of sequence-dependent stability of RecA filament

RecA is a DNA-dependent ATPase and mediates homologous recombination by first forming a filament on a single-stranded (ss) DNA. RecA binds preferentially to TGG repeat sequence, which resembles the recombination hot spot Chi (5′-GCTGGTGG-3′) and is the most frequent pattern (GTG) of the codon usage...

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Detalles Bibliográficos
Autores principales:	Kim, Sung Hyun, Joo, Chirlmin, Ha, Taekjip, Kim, Doseok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763553/ https://www.ncbi.nlm.nih.gov/pubmed/23804763 http://dx.doi.org/10.1093/nar/gkt570

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