Single molecule quantitation and sequencing of rare translocations using microfluidic nested digital PCR

Cancers are heterogeneous and genetically unstable. New methods are needed that provide the sensitivity and specificity to query single cells at the genetic loci that drive cancer progression, thereby enabling researchers to study the progression of individual tumors. Here, we report the development...

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Detalles Bibliográficos
Autores principales: Shuga, Joe, Zeng, Yong, Novak, Richard, Lan, Qing, Tang, Xiaojiang, Rothman, Nathaniel, Vermeulen, Roel, Li, Laiyu, Hubbard, Alan, Zhang, Luoping, Mathies, Richard A., Smith, Martyn T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763562/
https://www.ncbi.nlm.nih.gov/pubmed/23873959
http://dx.doi.org/10.1093/nar/gkt613

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