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Heat Shock Protein 90 and Role of Its Chemical Inhibitors in Treatment of Hematologic Malignancies

Heat shock protein 90 (Hsp90) is a conserved and constitutively expressed molecular chaperone and it has been shown to stabilize oncoproteins and facilitate cancer development. Hsp90 has been considered as a therapeutic target for cancers and three classes of Hsp90 inhibitors have been developed: (1...

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Detalles Bibliográficos
Autores principales:	Ho, Ngoc, Li, Adam, Li, Shaoguang, Zhang, Haojian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763672/ https://www.ncbi.nlm.nih.gov/pubmed/24280675 http://dx.doi.org/10.3390/ph5080779

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