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Knockdown of Diacylglycerol Kinase Delta Inhibits Adipocyte Differentiation and Alters Lipid Synthesis

OBJECTIVE: Decreased expression of diacylglycerol kinase delta (DGKδ) has been linked to insulin resistance in humans and mice and is abundantly expressed in adipose tissue. We therefore examined its role in adipogenesis. DESIGN AND METHODS: We generated 3T3-L1 preadipocytes in which DGKδ expression...

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Detalles Bibliográficos
Autores principales:	LOWE, Christopher E., ZHANG, Qifeng, DENNIS, Rowena J., AUBRY, Evelyne A., O’RAHILLY, Stephen, WAKELAM, Michael J.O., ROCHFORD, Justin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763967/ https://www.ncbi.nlm.nih.gov/pubmed/23703849 http://dx.doi.org/10.1002/oby.20297

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