Regulation of Hippocampal cGMP Levels as a Candidate to Treat Cognitive Deficits in Huntington’s Disease

Huntington’s disease (HD) patients and mouse models show learning and memory impairment associated with hippocampal dysfunction. The neuronal nitric oxide synthase/3',5'-cyclic guanosine monophosphate (nNOS/cGMP) pathway is implicated in synaptic plasticity, and in learning and memory proc...

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Detalles Bibliográficos
Autores principales: Saavedra, Ana, Giralt, Albert, Arumí, Helena, Alberch, Jordi, Pérez-Navarro, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764028/
https://www.ncbi.nlm.nih.gov/pubmed/24040016
http://dx.doi.org/10.1371/journal.pone.0073664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764028/
https://www.ncbi.nlm.nih.gov/pubmed/24040016
http://dx.doi.org/10.1371/journal.pone.0073664

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