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Regulation of Hippocampal cGMP Levels as a Candidate to Treat Cognitive Deficits in Huntington’s Disease

Huntington’s disease (HD) patients and mouse models show learning and memory impairment associated with hippocampal dysfunction. The neuronal nitric oxide synthase/3',5'-cyclic guanosine monophosphate (nNOS/cGMP) pathway is implicated in synaptic plasticity, and in learning and memory proc...

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Detalles Bibliográficos
Autores principales:	Saavedra, Ana, Giralt, Albert, Arumí, Helena, Alberch, Jordi, Pérez-Navarro, Esther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764028/ https://www.ncbi.nlm.nih.gov/pubmed/24040016 http://dx.doi.org/10.1371/journal.pone.0073664

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