Proteasome Inhibitors Block DNA Repair and Radiosensitize Non-Small Cell Lung Cancer

Despite optimal radiation therapy (RT), chemotherapy and/or surgery, a majority of patients with locally advanced non-small cell lung cancer (NSCLC) fail treatment. To identify novel gene targets for improved tumor control, we performed whole genome RNAi screens to identify knockdowns that most repr...

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Detalles Bibliográficos
Autores principales: Cron, Kyle R., Zhu, Kaya, Kushwaha, Deepa S., Hsieh, Grace, Merzon, Dmitry, Rameseder, Jonathan, Chen, Clark C., D’Andrea, Alan D., Kozono, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764058/
https://www.ncbi.nlm.nih.gov/pubmed/24040035
http://dx.doi.org/10.1371/journal.pone.0073710

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