Cargando…
Grape Extracts Inhibit Multiple Events in the Cell Biology of Cholera Intoxication
Vibrio cholerae produces cholera toxin (CT), an AB(5) protein toxin that is primarily responsible for the profuse watery diarrhea of cholera. CT is secreted into the extracellular milieu, but the toxin attacks its Gsα target within the cytosol of a host cell. Thus, CT must cross a cellular membrane...
Autores principales: | Reddy, Srikar, Taylor, Michael, Zhao, Mojun, Cherubin, Patrick, Geden, Sandra, Ray, Supriyo, Francis, David, Teter, Ken |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764128/ https://www.ncbi.nlm.nih.gov/pubmed/24039929 http://dx.doi.org/10.1371/journal.pone.0073390 |
Ejemplares similares
-
A Therapeutic Chemical Chaperone Inhibits Cholera Intoxication and Unfolding/Translocation of the Cholera Toxin A1 Subunit
por: Taylor, Michael, et al.
Publicado: (2011) -
Inhibition of Cholera Toxin and Other AB Toxins by Polyphenolic Compounds
por: Cherubin, Patrick, et al.
Publicado: (2016) -
Substrate-Induced Unfolding of Protein Disulfide Isomerase Displaces the Cholera Toxin A1 Subunit from Its Holotoxin
por: Taylor, Michael, et al.
Publicado: (2014) -
Protein disulfide isomerase does not act as an unfoldase in the disassembly of cholera toxin
por: Cherubin, Patrick, et al.
Publicado: (2018) -
Quercetin-3-Rutinoside Blocks the Disassembly of Cholera Toxin by Protein Disulfide Isomerase
por: Guyette, Jessica, et al.
Publicado: (2019)