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Patterns of Linkage Disequilibrium of LRRK2 across Different Races: Implications for Genetic Association Studies

Genome Wide Association Studies (GWASs) have identified trait-associated polymorphisms via a hypothesis-free approach. However, it is challenging when attempting to reproduce GWAS findings in different populations as it fundamentally relies on the similar patterns of linkage disequilibrium (LD) betw...

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Detalles Bibliográficos
Autores principales: Li, Huihua, Teo, Yik Ying, Tan, Eng King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764133/
https://www.ncbi.nlm.nih.gov/pubmed/24040382
http://dx.doi.org/10.1371/journal.pone.0075041