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Integrin – Dependent Mechanotransduction in Mechanically Stimulated Human Annulus Fibrosus Cells: Evidence for an Alternative Mechanotransduction Pathway Operating with Degeneration

Intervertebral disc (IVD) cells derived from degenerate tissue respond aberrantly to mechanical stimuli, potentially due to altered mechanotransduction pathways. Elucidation of the altered, or alternative, mechanotransduction pathways operating with degeneration could yield novel targets for the tre...

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Detalles Bibliográficos
Autores principales: Gilbert, Hamish T. J., Nagra, Navraj S., Freemont, Anthony J., Millward-Sadler, Sarah J., Hoyland, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764176/
https://www.ncbi.nlm.nih.gov/pubmed/24039840
http://dx.doi.org/10.1371/journal.pone.0072994