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Integrin – Dependent Mechanotransduction in Mechanically Stimulated Human Annulus Fibrosus Cells: Evidence for an Alternative Mechanotransduction Pathway Operating with Degeneration
Intervertebral disc (IVD) cells derived from degenerate tissue respond aberrantly to mechanical stimuli, potentially due to altered mechanotransduction pathways. Elucidation of the altered, or alternative, mechanotransduction pathways operating with degeneration could yield novel targets for the tre...
Autores principales: | Gilbert, Hamish T. J., Nagra, Navraj S., Freemont, Anthony J., Millward-Sadler, Sarah J., Hoyland, Judith A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764176/ https://www.ncbi.nlm.nih.gov/pubmed/24039840 http://dx.doi.org/10.1371/journal.pone.0072994 |
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