Cargando…

Mitochondrial iron transport and homeostasis in plants

Iron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells. Mitochondria represent a significant iron sink within cells, as iron is...

Descripción completa

Detalles Bibliográficos
Autores principales: Jain, Anshika, Connolly, Erin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764374/
https://www.ncbi.nlm.nih.gov/pubmed/24046773
http://dx.doi.org/10.3389/fpls.2013.00348
_version_ 1782283143671185408
author Jain, Anshika
Connolly, Erin L.
author_facet Jain, Anshika
Connolly, Erin L.
author_sort Jain, Anshika
collection PubMed
description Iron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells. Mitochondria represent a significant iron sink within cells, as iron is required for the proper functioning of respiratory chain protein complexes. Mitochondria are a site of Fe–S cluster synthesis, and possibly heme synthesis as well. Here we review recent insights into the molecular mechanisms controlling mitochondrial iron transport and homeostasis. We focus on the recent identification of a mitochondrial iron uptake transporter in rice and a possible role for metalloreductases in iron uptake by mitochondria. In addition, we highlight recent advances in mitochondrial iron homeostasis with an emphasis on the roles of frataxin and ferritin in iron trafficking and storage within mitochondria.
format Online
Article
Text
id pubmed-3764374
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-37643742013-09-17 Mitochondrial iron transport and homeostasis in plants Jain, Anshika Connolly, Erin L. Front Plant Sci Plant Science Iron (Fe) is an essential nutrient for plants and although the mechanisms controlling iron uptake from the soil are relatively well understood, comparatively little is known about subcellular trafficking of iron in plant cells. Mitochondria represent a significant iron sink within cells, as iron is required for the proper functioning of respiratory chain protein complexes. Mitochondria are a site of Fe–S cluster synthesis, and possibly heme synthesis as well. Here we review recent insights into the molecular mechanisms controlling mitochondrial iron transport and homeostasis. We focus on the recent identification of a mitochondrial iron uptake transporter in rice and a possible role for metalloreductases in iron uptake by mitochondria. In addition, we highlight recent advances in mitochondrial iron homeostasis with an emphasis on the roles of frataxin and ferritin in iron trafficking and storage within mitochondria. Frontiers Media S.A. 2013-09-06 /pmc/articles/PMC3764374/ /pubmed/24046773 http://dx.doi.org/10.3389/fpls.2013.00348 Text en Copyright © Jain and Connolly. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Jain, Anshika
Connolly, Erin L.
Mitochondrial iron transport and homeostasis in plants
title Mitochondrial iron transport and homeostasis in plants
title_full Mitochondrial iron transport and homeostasis in plants
title_fullStr Mitochondrial iron transport and homeostasis in plants
title_full_unstemmed Mitochondrial iron transport and homeostasis in plants
title_short Mitochondrial iron transport and homeostasis in plants
title_sort mitochondrial iron transport and homeostasis in plants
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764374/
https://www.ncbi.nlm.nih.gov/pubmed/24046773
http://dx.doi.org/10.3389/fpls.2013.00348
work_keys_str_mv AT jainanshika mitochondrialirontransportandhomeostasisinplants
AT connollyerinl mitochondrialirontransportandhomeostasisinplants