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The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting
Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: A retrospective cohort study was conducted of CABG patients between 2002 and 20...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764432/ https://www.ncbi.nlm.nih.gov/pubmed/24013365 http://dx.doi.org/10.3389/fpubh.2013.00004 |
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author | Efird, Jimmy T. O’Neal, Wesley T. Anderson, Curtis A. O’Neal, Jason B. Kindell, Linda C. Ferguson, T. Bruce Chitwood, W. Randolph Kypson, Alan P. |
author_facet | Efird, Jimmy T. O’Neal, Wesley T. Anderson, Curtis A. O’Neal, Jason B. Kindell, Linda C. Ferguson, T. Bruce Chitwood, W. Randolph Kypson, Alan P. |
author_sort | Efird, Jimmy T. |
collection | PubMed |
description | Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: A retrospective cohort study was conducted of CABG patients between 2002 and 2011. Long-term survival was compared in patients with and without COPD and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. Results: A total of 984 (20%) patients had COPD (black n = 182; white n = 802) at the time of CABG (N = 4,801). The median follow-up for study participants was 4.4 years. COPD was observed to be a statistically significant predictor of decreased survival independent of race following CABG (no COPD: HR = 1.0; white COPD: adjusted HR = 1.9, 95% CI = 1.7–2.3; black COPD: adjusted HR = 1.6, 95% CI = 1.1–2.2). Conclusion: Contrary to the expected increased risk of mortality among black COPD patients in the general population, a similar survival disadvantage was not observed in our CABG population. |
format | Online Article Text |
id | pubmed-3764432 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-37644322013-09-06 The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting Efird, Jimmy T. O’Neal, Wesley T. Anderson, Curtis A. O’Neal, Jason B. Kindell, Linda C. Ferguson, T. Bruce Chitwood, W. Randolph Kypson, Alan P. Front Public Health Public Health Background: Chronic obstructive pulmonary disease (COPD) is a known predictor of decreased long-term survival after coronary artery bypass grafting (CABG). Differences in survival by race have not been examined. Methods: A retrospective cohort study was conducted of CABG patients between 2002 and 2011. Long-term survival was compared in patients with and without COPD and stratified by race. Hazard ratios (HR) and 95% confidence intervals (CI) were computed using a Cox regression model. Results: A total of 984 (20%) patients had COPD (black n = 182; white n = 802) at the time of CABG (N = 4,801). The median follow-up for study participants was 4.4 years. COPD was observed to be a statistically significant predictor of decreased survival independent of race following CABG (no COPD: HR = 1.0; white COPD: adjusted HR = 1.9, 95% CI = 1.7–2.3; black COPD: adjusted HR = 1.6, 95% CI = 1.1–2.2). Conclusion: Contrary to the expected increased risk of mortality among black COPD patients in the general population, a similar survival disadvantage was not observed in our CABG population. Frontiers Media S.A. 2013-04-15 /pmc/articles/PMC3764432/ /pubmed/24013365 http://dx.doi.org/10.3389/fpubh.2013.00004 Text en Copyright © 2013 Efird, O’Neal, Anderson, O’Neal, Kindell, Ferguson, Chitwood and Kypson. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and source are credited and subject to any copyright notices concerning any third-party graphics etc. |
spellingShingle | Public Health Efird, Jimmy T. O’Neal, Wesley T. Anderson, Curtis A. O’Neal, Jason B. Kindell, Linda C. Ferguson, T. Bruce Chitwood, W. Randolph Kypson, Alan P. The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting |
title | The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting |
title_full | The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting |
title_fullStr | The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting |
title_full_unstemmed | The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting |
title_short | The Effect of Race and Chronic Obstructive Pulmonary Disease on Long-Term Survival after Coronary Artery Bypass Grafting |
title_sort | effect of race and chronic obstructive pulmonary disease on long-term survival after coronary artery bypass grafting |
topic | Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764432/ https://www.ncbi.nlm.nih.gov/pubmed/24013365 http://dx.doi.org/10.3389/fpubh.2013.00004 |
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