Burst activity and ultrafast activation kinetics of Ca(V)1.3 Ca(2+) channels support presynaptic activity in adult gerbil hair cell ribbon synapses

Auditory information transfer to afferent neurons relies on precise triggering of neurotransmitter release at the inner hair cell (IHC) ribbon synapses by Ca(2+) entry through Ca(V)1.3 Ca(2+) channels. Despite the crucial role of Ca(V)1.3 Ca(2+) channels in governing synaptic vesicle fusion, their e...

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Detalles Bibliográficos
Autores principales: Zampini, Valeria, Johnson, Stuart L, Franz, Christoph, Knipper, Marlies, Holley, Matthew C, Magistretti, Jacopo, Masetto, Sergio, Marcotti, Walter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Neuroscience: Cellular/Molecular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764630/
https://www.ncbi.nlm.nih.gov/pubmed/23713031
http://dx.doi.org/10.1113/jphysiol.2013.251272

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