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Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma

Non-Hodgkin lymphoma (NHL) accounts for 10% of pediatric malignancies and is the third most common malignancy in childhood. We report a previous healthy 3-year-old boy with stage IV Burkitt lymphoma presenting with acute visual loss. In funduscopy his pupils were fixed at 6 mm in diameter without li...

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Autores principales: Kourti, Maria, Mantadakis, Elpidoforos, Anastasiou, Athanassia, Koliouskas, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764753/
https://www.ncbi.nlm.nih.gov/pubmed/24049296
http://dx.doi.org/10.4103/0971-5851.116188
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author Kourti, Maria
Mantadakis, Elpidoforos
Anastasiou, Athanassia
Koliouskas, Dimitrios
author_facet Kourti, Maria
Mantadakis, Elpidoforos
Anastasiou, Athanassia
Koliouskas, Dimitrios
author_sort Kourti, Maria
collection PubMed
description Non-Hodgkin lymphoma (NHL) accounts for 10% of pediatric malignancies and is the third most common malignancy in childhood. We report a previous healthy 3-year-old boy with stage IV Burkitt lymphoma presenting with acute visual loss. In funduscopy his pupils were fixed at 6 mm in diameter without light perception. He started therapy according to the UKCCSG 9003 protocol. The boy didn’t show any visual improvement but some slight light perception despite his partial remission after CYVE II. He died of neutropenic septicemia before his scheduled radiotherapy. In conclusion, loss of vision is a rare presenting sign in NHL. Differential diagnosis is crucial as early diagnosis and effective treatment are important for survival as well as for visual restoration.
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spelling pubmed-37647532013-09-18 Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma Kourti, Maria Mantadakis, Elpidoforos Anastasiou, Athanassia Koliouskas, Dimitrios Indian J Med Paediatr Oncol Case Report Non-Hodgkin lymphoma (NHL) accounts for 10% of pediatric malignancies and is the third most common malignancy in childhood. We report a previous healthy 3-year-old boy with stage IV Burkitt lymphoma presenting with acute visual loss. In funduscopy his pupils were fixed at 6 mm in diameter without light perception. He started therapy according to the UKCCSG 9003 protocol. The boy didn’t show any visual improvement but some slight light perception despite his partial remission after CYVE II. He died of neutropenic septicemia before his scheduled radiotherapy. In conclusion, loss of vision is a rare presenting sign in NHL. Differential diagnosis is crucial as early diagnosis and effective treatment are important for survival as well as for visual restoration. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3764753/ /pubmed/24049296 http://dx.doi.org/10.4103/0971-5851.116188 Text en Copyright: © Indian Journal of Medical and Paediatric Oncology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kourti, Maria
Mantadakis, Elpidoforos
Anastasiou, Athanassia
Koliouskas, Dimitrios
Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma
title Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma
title_full Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma
title_fullStr Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma
title_full_unstemmed Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma
title_short Acute visual loss as the initial presentation in a child with systemic Burkitt lymphoma
title_sort acute visual loss as the initial presentation in a child with systemic burkitt lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764753/
https://www.ncbi.nlm.nih.gov/pubmed/24049296
http://dx.doi.org/10.4103/0971-5851.116188
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