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In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark
Cordia dichotoma Forst. f. bark, identified as botanical source of Shleshmataka in Ayurvedic pharmacopoeia. Present investigation was undertaken to evaluate possible antioxidant potential of methanolic and butanol extract of C. dichotoma bark. In vitro antioxidant activity of methanolic and butanol...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764870/ https://www.ncbi.nlm.nih.gov/pubmed/24049418 http://dx.doi.org/10.4103/0974-8520.115451 |
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author | Nariya, Pankaj B. Bhalodia, Nayan R. Shukla, Vinay J. Acharya, Rabinarayan Nariya, Mukesh B. |
author_facet | Nariya, Pankaj B. Bhalodia, Nayan R. Shukla, Vinay J. Acharya, Rabinarayan Nariya, Mukesh B. |
author_sort | Nariya, Pankaj B. |
collection | PubMed |
description | Cordia dichotoma Forst. f. bark, identified as botanical source of Shleshmataka in Ayurvedic pharmacopoeia. Present investigation was undertaken to evaluate possible antioxidant potential of methanolic and butanol extract of C. dichotoma bark. In vitro antioxidant activity of methanolic and butanol extract was determined by 1,1, diphenyl–2, picrylhydrazyl (DPPH) free radical scavenging assay. The extracts were also evaluated for their phenolic contents and antioxidant activity. Phenolic content was measured using Folin–Ciocalteu reagent and was calculated as Gallic acid equivalents. Antiradical activity of methanolic extract was measured by DPPH assay and was compared to ascorbic acid and ferric reducing power of the extract was evaluated by Oyaizu method. In the present study three in vitro models were used to evaluate antioxidant activity. The first two methods were for direct measurement of radical scavenging activity and remaining one method evaluated the reducing power. The present study revealed that the C. dichotoma bark has significant radical scavenging activity. |
format | Online Article Text |
id | pubmed-3764870 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37648702013-09-18 In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark Nariya, Pankaj B. Bhalodia, Nayan R. Shukla, Vinay J. Acharya, Rabinarayan Nariya, Mukesh B. Ayu Pharmacological Study Cordia dichotoma Forst. f. bark, identified as botanical source of Shleshmataka in Ayurvedic pharmacopoeia. Present investigation was undertaken to evaluate possible antioxidant potential of methanolic and butanol extract of C. dichotoma bark. In vitro antioxidant activity of methanolic and butanol extract was determined by 1,1, diphenyl–2, picrylhydrazyl (DPPH) free radical scavenging assay. The extracts were also evaluated for their phenolic contents and antioxidant activity. Phenolic content was measured using Folin–Ciocalteu reagent and was calculated as Gallic acid equivalents. Antiradical activity of methanolic extract was measured by DPPH assay and was compared to ascorbic acid and ferric reducing power of the extract was evaluated by Oyaizu method. In the present study three in vitro models were used to evaluate antioxidant activity. The first two methods were for direct measurement of radical scavenging activity and remaining one method evaluated the reducing power. The present study revealed that the C. dichotoma bark has significant radical scavenging activity. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3764870/ /pubmed/24049418 http://dx.doi.org/10.4103/0974-8520.115451 Text en Copyright: © AYU (An International Quarterly Journal of Research in Ayurveda) http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Pharmacological Study Nariya, Pankaj B. Bhalodia, Nayan R. Shukla, Vinay J. Acharya, Rabinarayan Nariya, Mukesh B. In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark |
title | In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark |
title_full | In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark |
title_fullStr | In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark |
title_full_unstemmed | In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark |
title_short | In vitro evaluation of antioxidant activity of Cordia dichotoma (Forst f.) bark |
title_sort | in vitro evaluation of antioxidant activity of cordia dichotoma (forst f.) bark |
topic | Pharmacological Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764870/ https://www.ncbi.nlm.nih.gov/pubmed/24049418 http://dx.doi.org/10.4103/0974-8520.115451 |
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