Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis

Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone...

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Autores principales: Riad, Hassan, Mannai, Haya Al, Mansour, Khalid, Qaatri, Khalifa Al, Dosari, Sharifa Al, Obaidaly, Amina Al, Sultan, Emad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Published online: August, 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764942/
https://www.ncbi.nlm.nih.gov/pubmed/24019775
http://dx.doi.org/10.1159/000354767
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author Riad, Hassan
Mannai, Haya Al
Mansour, Khalid
Qaatri, Khalifa Al
Dosari, Sharifa Al
Obaidaly, Amina Al
Sultan, Emad
author_facet Riad, Hassan
Mannai, Haya Al
Mansour, Khalid
Qaatri, Khalifa Al
Dosari, Sharifa Al
Obaidaly, Amina Al
Sultan, Emad
author_sort Riad, Hassan
collection PubMed
description Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone (diphencyprone, DCP) is used in the treatment of alopecia areata and may induce vitiligo in some patients. We report on one case of vitiligo that was induced by DCP during therapy for alopecia universalis. Alopecia areata and vitiligo share many susceptibility genes. Follicular melanocyte destruction may represent the link between the two diseases.
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spelling pubmed-37649422013-09-09 Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis Riad, Hassan Mannai, Haya Al Mansour, Khalid Qaatri, Khalifa Al Dosari, Sharifa Al Obaidaly, Amina Al Sultan, Emad Case Rep Dermatol Published online: August, 2013 Alopecia areata and vitiligo are autoimmune diseases, both associated with multiple autoimmune comorbidities. Many studies show colocalization of these diseases at the same anatomical site. Here, we have a case where both disorders were reported to present in the same patient. Diphenylcyclopropenone (diphencyprone, DCP) is used in the treatment of alopecia areata and may induce vitiligo in some patients. We report on one case of vitiligo that was induced by DCP during therapy for alopecia universalis. Alopecia areata and vitiligo share many susceptibility genes. Follicular melanocyte destruction may represent the link between the two diseases. S. Karger AG 2013-08-17 /pmc/articles/PMC3764942/ /pubmed/24019775 http://dx.doi.org/10.1159/000354767 Text en Copyright © 2013 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published online: August, 2013
Riad, Hassan
Mannai, Haya Al
Mansour, Khalid
Qaatri, Khalifa Al
Dosari, Sharifa Al
Obaidaly, Amina Al
Sultan, Emad
Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
title Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
title_full Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
title_fullStr Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
title_full_unstemmed Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
title_short Diphenylcyclopropenone-Induced Vitiligo in a Patient with Alopecia Universalis
title_sort diphenylcyclopropenone-induced vitiligo in a patient with alopecia universalis
topic Published online: August, 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764942/
https://www.ncbi.nlm.nih.gov/pubmed/24019775
http://dx.doi.org/10.1159/000354767
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