Bevacizumab is Effective for Recurrent Papillary Tumor of the Pineal Region: First Report

Papillary tumor of the pineal region (PTPR) is a rare brain tumor that probably arises from ependymal cells. There are no known systemic treatments for PTPR once it is refractory to surgery and radiation. We present the first case of a durable radiographic and clinical response of a PTPR to bevacizu...

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Detalles Bibliográficos
Autores principales: Cohen, Adam L., Salzman, Karen, Palmer, Cheryl, Jensen, Randy, Colman, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Published online: August, 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764969/
https://www.ncbi.nlm.nih.gov/pubmed/24019784
http://dx.doi.org/10.1159/000354753
Descripción
Sumario:Papillary tumor of the pineal region (PTPR) is a rare brain tumor that probably arises from ependymal cells. There are no known systemic treatments for PTPR once it is refractory to surgery and radiation. We present the first case of a durable radiographic and clinical response of a PTPR to bevacizumab, an antibody against vascular endothelial growth factor, despite multiple prior treatments. Bevacizumab may be an effective treatment for PTPR.

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