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Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients
Diabetic ulcers and pressure ulcers represent a more frequent cause of chronic wounds in aging populations. It is estimated that approximately 15% of the diabetic population will develop diabetic ulcers during their life and over half of these patients develop an infection, often osteomyelitis, with...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764980/ https://www.ncbi.nlm.nih.gov/pubmed/24020011 http://dx.doi.org/10.1177/2041731413502663 |
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author | De Angelis, Barbara Gentile, Pietro Agovino, Annarita Migner, Alessia Orlandi, Fabrizio Delogu, Pamela Cervelli, Valerio |
author_facet | De Angelis, Barbara Gentile, Pietro Agovino, Annarita Migner, Alessia Orlandi, Fabrizio Delogu, Pamela Cervelli, Valerio |
author_sort | De Angelis, Barbara |
collection | PubMed |
description | Diabetic ulcers and pressure ulcers represent a more frequent cause of chronic wounds in aging populations. It is estimated that approximately 15% of the diabetic population will develop diabetic ulcers during their life and over half of these patients develop an infection, often osteomyelitis, with 20% requiring amputation. The authors report a case of a 65-year-old woman affected by a post-traumatic loss of substance due to road accidents with soft tissue exposure (comprising muscle tendon) of the left knee combined with the fracture of the right fibula previously subjected to surgery and reconstruction of muscle tendon. The patient was affected by diabetes type II, hypertension, and ischemic heart disease. In 2008, she underwent a double bypass surgery and coronary angioplasty. Initially, the patient was treated with cycles of advanced dressings, with fibrinolytic ointments, hydrocolloid, and subsequently, when the bottom began granulated with fibrinolytic and idrocellulosa, Hydrofibra-Ag, and Ag-alginate, three times a week for 30 days. In the second step, the authors decided to treat the ulcer with the MATRIDERM system and auto skin graft. Following the first treatment, 7 days after the procedure, the authors found the reduction of the loss of substance until its complete closure. The wound’s infection was evaluated by a buffer negative confirmation performed every 2 weeks four times. We obtained decrease of limb edema and full functional rehabilitation. The skin appeared renovated, with volume restoration and an improvement of the texture. |
format | Online Article Text |
id | pubmed-3764980 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-37649802013-09-09 Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients De Angelis, Barbara Gentile, Pietro Agovino, Annarita Migner, Alessia Orlandi, Fabrizio Delogu, Pamela Cervelli, Valerio J Tissue Eng Article Diabetic ulcers and pressure ulcers represent a more frequent cause of chronic wounds in aging populations. It is estimated that approximately 15% of the diabetic population will develop diabetic ulcers during their life and over half of these patients develop an infection, often osteomyelitis, with 20% requiring amputation. The authors report a case of a 65-year-old woman affected by a post-traumatic loss of substance due to road accidents with soft tissue exposure (comprising muscle tendon) of the left knee combined with the fracture of the right fibula previously subjected to surgery and reconstruction of muscle tendon. The patient was affected by diabetes type II, hypertension, and ischemic heart disease. In 2008, she underwent a double bypass surgery and coronary angioplasty. Initially, the patient was treated with cycles of advanced dressings, with fibrinolytic ointments, hydrocolloid, and subsequently, when the bottom began granulated with fibrinolytic and idrocellulosa, Hydrofibra-Ag, and Ag-alginate, three times a week for 30 days. In the second step, the authors decided to treat the ulcer with the MATRIDERM system and auto skin graft. Following the first treatment, 7 days after the procedure, the authors found the reduction of the loss of substance until its complete closure. The wound’s infection was evaluated by a buffer negative confirmation performed every 2 weeks four times. We obtained decrease of limb edema and full functional rehabilitation. The skin appeared renovated, with volume restoration and an improvement of the texture. SAGE Publications 2013-08-26 /pmc/articles/PMC3764980/ /pubmed/24020011 http://dx.doi.org/10.1177/2041731413502663 Text en © The Author(s) 2013 http://creativecommons.org/licenses/by-nc/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article De Angelis, Barbara Gentile, Pietro Agovino, Annarita Migner, Alessia Orlandi, Fabrizio Delogu, Pamela Cervelli, Valerio Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients |
title | Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients |
title_full | Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients |
title_fullStr | Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients |
title_full_unstemmed | Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients |
title_short | Chronic ulcers: MATRIDERM(®) system in smoker, cardiopathic, and diabetic patients |
title_sort | chronic ulcers: matriderm(®) system in smoker, cardiopathic, and diabetic patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764980/ https://www.ncbi.nlm.nih.gov/pubmed/24020011 http://dx.doi.org/10.1177/2041731413502663 |
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