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Identification of piggyBac-mediated insertions in Plasmodium berghei by next generation sequencing

BACKGROUND: The piggyBac transposon system provides a powerful forward genetics tool to study gene function in Plasmodium parasites via random insertion mutagenesis and phenotypic screening. The identification of genotype of piggyBac mutants in the Plasmodium genome is thus an indispensable step in...

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Detalles Bibliográficos
Autores principales: Cao, Yi, Rui, Bing, Wellems, Dianne L, Li, Mingxing, Chen, Biaobang, Zhang, Dongmei, Pan, Weiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765144/
https://www.ncbi.nlm.nih.gov/pubmed/23961915
http://dx.doi.org/10.1186/1475-2875-12-287