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Differential Expression of IL-17, 22 and 23 in the Progression of Colorectal Cancer in Patients with K-ras Mutation: Ras Signal Inhibition and Crosstalk with GM-CSF and IFN-γ

Recent studies have suggested that aberrant K-ras signaling is responsible for triggering immunological responses and inflammation-driven tumorigenesis. Interleukins IL-17, IL-22, and IL-23 have been reported in various types of malignancies, but the exact mechanistic role of these molecules remains...

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Detalles Bibliográficos
Autores principales: Petanidis, Savvas, Anestakis, Doxakis, Argyraki, Maria, Hadzopoulou-Cladaras, Margarita, Salifoglou, Athanasios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765247/
https://www.ncbi.nlm.nih.gov/pubmed/24040001
http://dx.doi.org/10.1371/journal.pone.0073616