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Loss of the BRCA1-Interacting Helicase BRIP1 Results in Abnormal Mammary Acinar Morphogenesis

BRIP1 is a DNA helicase that directly interacts with the C-terminal BRCT repeat of the breast cancer susceptibility protein BRCA1 and plays an important role in BRCA1-dependent DNA repair and DNA damage–induced checkpoint control. Recent studies implicate BRIP1 as a moderate/low-penetrance breast ca...

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Detalles Bibliográficos
Autores principales:	Daino, Kazuhiro, Imaoka, Tatsuhiko, Morioka, Takamitsu, Tani, Shusuke, Iizuka, Daisuke, Nishimura, Mayumi, Shimada, Yoshiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765252/ https://www.ncbi.nlm.nih.gov/pubmed/24040146 http://dx.doi.org/10.1371/journal.pone.0074013

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