Haplotype phasing after joint estimation of recombination and linkage disequilibrium in breeding populations

A novel method for haplotype phasing in families after joint estimation of recombination fraction and linkage disequilibrium is developed. Results from Monte Carlo computer simulations show that the newly developed E.M. algorithm is accurate if true recombination fraction is 0 even for single famili...

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Detalles Bibliográficos
Autores principales: Gomez-Raya, Luis, Hulse, Amanda M, Thain, David, Rauw, Wendy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765333/
https://www.ncbi.nlm.nih.gov/pubmed/23916349
http://dx.doi.org/10.1186/2049-1891-4-30

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