TGFβ and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation

BACKGROUND: CCN2/CTGF is an established effector of TGFβ driven responses in diabetic nephropathy. We have identified an interaction between CCN2 and TGFβ leading to altered phenotypic differentiation and inhibited cellular migration. Here we determine the gene expression profile associated with thi...

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Detalles Bibliográficos
Autores principales: Faherty, Noel, O’Donovan, Helen, Kavanagh, David, Madden, Stephen, McKay, Gareth J, Maxwell, Alexander P, Martin, Finian, Godson, Catherine, Crean, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765338/
https://www.ncbi.nlm.nih.gov/pubmed/23902294
http://dx.doi.org/10.1186/1471-2164-14-525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765338/
https://www.ncbi.nlm.nih.gov/pubmed/23902294
http://dx.doi.org/10.1186/1471-2164-14-525

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