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TGFβ and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation
BACKGROUND: CCN2/CTGF is an established effector of TGFβ driven responses in diabetic nephropathy. We have identified an interaction between CCN2 and TGFβ leading to altered phenotypic differentiation and inhibited cellular migration. Here we determine the gene expression profile associated with thi...
Autores principales: | Faherty, Noel, O’Donovan, Helen, Kavanagh, David, Madden, Stephen, McKay, Gareth J, Maxwell, Alexander P, Martin, Finian, Godson, Catherine, Crean, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765338/ https://www.ncbi.nlm.nih.gov/pubmed/23902294 http://dx.doi.org/10.1186/1471-2164-14-525 |
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