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Computational estimation of tricarboxylic acid cycle fluxes using noisy NMR data from cardiac biopsies
BACKGROUND: The aerobic energy metabolism of cardiac muscle cells is of major importance for the contractile function of the heart. Because energy metabolism is very heterogeneously distributed in heart tissue, especially during coronary disease, a method to quantify metabolic fluxes in small tissue...
Autores principales: | Hettling, Hannes, Alders, David J C, Heringa, Jaap, Binsl, Thomas W, Groeneveld, A B Johan, van Beek, Johannes H G M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765389/ https://www.ncbi.nlm.nih.gov/pubmed/23965343 http://dx.doi.org/10.1186/1752-0509-7-82 |
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