Germline deletions in the EPCAM gene as a cause of Lynch syndrome – literature review

Lynch syndrome (clinically referred to as HNPCC – Hereditary Non-Polyposis Colorectal Cancer) is a frequent, autosomal, dominantly-inherited cancer predisposition syndrome caused by various germline alterations that affect DNA mismatch repair genes, mainly MLH1 and MSH2. Patients inheriting this pre...

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Detalles Bibliográficos
Autores principales: Tutlewska, Katarzyna, Lubinski, Jan, Kurzawski, Grzegorz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765447/
https://www.ncbi.nlm.nih.gov/pubmed/23938213
http://dx.doi.org/10.1186/1897-4287-11-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765447/
https://www.ncbi.nlm.nih.gov/pubmed/23938213
http://dx.doi.org/10.1186/1897-4287-11-9

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