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Cohesin loading factor Nipbl localizes to chromosome axes during mammalian meiotic prophase

BACKGROUND: Sister chromatid cohesion mediated by the cohesin complex is essential for accurate chromosome segregation during mitosis and meiosis. Loading of cohesin onto chromosomes is dependent on another protein complex called kollerin, containing Nipbl/Scc2 and Mau2/Scc4. Nipbl is an evolutionar...

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Detalles Bibliográficos
Autores principales: Kuleszewicz, Katarzyna, Fu, Xiangwei, Kudo, Nobuaki R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765518/
https://www.ncbi.nlm.nih.gov/pubmed/23967866
http://dx.doi.org/10.1186/1747-1028-8-12