Cargando…

Synthesis and evaluation of bifunctional sGC regulators

Detalles Bibliográficos
Autores principales:	Chrominski, Mikolaj, Gryko, Dorota, Sharina, Iraida, Martin, Emil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Poster Presentation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765572/ http://dx.doi.org/10.1186/2050-6511-14-S1-P15

Ejemplares similares

Gemfibrozil as a potential heme-independent sGC activator
por: Sobolevsky, Michael, et al.
Publicado: (2011)

Alternative splicing of α1 and β1 sGC genes is altered in aortic disease
por: Martin, Emil, et al.
Publicado: (2013)

G-protein signaling modulator 1 is a modifier of sGC-dependent vascular response
por: Britton, George, et al.
Publicado: (2013)

New vitamin B(12) derivatives activates sGC
por: Gryko, Dorota, et al.
Publicado: (2011)

G-protein regulator LGN inhibits the activity of soluble guanylyl cyclase
por: Chauhan, Swati, et al.
Publicado: (2011)

Lack of correlation between sGC subunit expression and sGC activity in cerebral development is due to non-heterodimerizing subunits in vivo
por: Haase, Nadine, et al.
Publicado: (2009)

Genetic silencing of sGC β1 in cancer: role of epigenetic regulation
por: Sotolongo, Alex, et al.
Publicado: (2013)

Molecular aspects of sGC regulation
por: Marletta, Michael A, et al.
Publicado: (2011)

Structural insights into sGC
por: Akker, Focco van den, et al.
Publicado: (2009)

sGC activators and stimulators attenuate ischemia/reperfusion injury of the lung
por: Egemnazarov, Bakytbek, et al.
Publicado: (2009)

A molecular view of the regulation of sGC activity
por: Marletta, Michael A, et al.
Publicado: (2009)

Targeting native and apo-sGC
por: Struthers, Mary, et al.
Publicado: (2013)

Platelet inhibitory effects of the NO independent sGC stimulator riociguat (Bay 63-2561)
por: Reiss, Cora, et al.
Publicado: (2013)

Conformational changes involved in sGC activation
por: Marletta, Michael A, et al.
Publicado: (2013)

New clinical results with sGC stimulators
por: Behr, Jürgen
Publicado: (2011)

Structural insights into sGC activation by different activators
por: van den Akker, Focco, et al.
Publicado: (2011)

Cardioprotective effects in aged spontaneously hypertensive rats due to chronic stimulation/activation of sGC without hypotension
por: Jones, Emma S, et al.
Publicado: (2009)

sGCα(1)β(1 )attenuates cardiac dysfunction and mortality in murine inflammatory shock models
por: Buys, Emmanuel S, et al.
Publicado: (2009)

Relaxant effect of BAY 41-2272 and BAY 58-2667 in the gastrointestinal tract of apo-sGC mice
por: Cosyns, Sarah, et al.
Publicado: (2011)

Genetic modifiers of hypertension in sGC-deficient mice
por: Buys, Emmanuel
Publicado: (2013)

sGC redox regulation and asthma
por: Stuehr, Dennis J, et al.
Publicado: (2015)

Increases survival by apo-sGC activation via post-stroke blood brain barrier stabilisation and anti-inflammation
por: Langhauser, Friedericke, et al.
Publicado: (2013)

Direct evidence for close proximity of catalytic and regulatory domains of heterodimeric sGC based on fluorescence resonance energy transfer
por: Haase, Tobias, et al.
Publicado: (2009)

Effect of L-carnitine supplementation on the sGC/cGMP pathway in vascular relaxing responses from exercised rats
por: Priviero, Fernanda BM, et al.
Publicado: (2009)

sGCα(1)-deficient mice: a novel murine model of spontaneous primary open angle glaucoma
por: Buys, Emmanuel S, et al.
Publicado: (2011)

Hypoxic NO-donor nitrite protects sGC-dependently against morbidity and mortality associated with sterile inflammatory shock in mice
por: Cauwels, A, et al.
Publicado: (2011)

Comparison of different vasodilators, endothelin antagonist, PDE5 inhibitior and sGC stimulators, in an animal model of secondary pulmonary hypertension: effects on “desaturation”
por: Becker, Eva Maria, et al.
Publicado: (2011)

L-arginine supplementation improves aortic vascular relaxation via NO-independent sGC/cGMP signaling in exercised rats
por: Zanesco, Angelina, et al.
Publicado: (2009)

Antihypertrophic actions of NO-independent soluble guanylyl cyclase (sGC) ligands BAY 41-2272 and BAY 58-2667 in vitro
por: Ritchie, Rebecca, et al.
Publicado: (2009)

Phenotypes of sGC mutant mice in basic conditions, disease and shock
por: Brouckaert, Peter, et al.
Publicado: (2009)

Additional stimulation of sGC on top of standard treatment with ARB`s may offer a new therapeutic approach for the treatment of diabetic nephropathy resistant to ARB treatment alone
por: Alter, Markus, et al.
Publicado: (2011)

Mechanisms driving heme insertion into apo-sGC during its maturation in cells
por: Stuehr, Dennis, et al.
Publicado: (2013)

A Zebrafish Drug-Repurposing Screen Reveals sGC-Dependent and sGC-Independent Pro-Inflammatory Activities of Nitric Oxide
por: Wittmann, Christine, et al.
Publicado: (2015)

Synergistic mutations in soluble guanylyl cyclase (sGC) reveal a key role for interfacial regions in the sGC activation mechanism
por: Childers, Kenneth C., et al.
Publicado: (2019)

Experimental evidence that a combination of sGC stimulator BAY 60-4552 and PDE5 inhibitor vardenafil could salvage ED-patients with insufficient response to PDE5 inhibitors after cavernous nerve injury
por: Oudot, Alexandra, et al.
Publicado: (2011)

Cellular Factors That Shape the Activity or Function of Nitric Oxide-Stimulated Soluble Guanylyl Cyclase
por: Sharina, Iraida, et al.
Publicado: (2023)

The clinical development of sGC modulators, riociguat and vericiguat
por: Misselwitz, Frank
Publicado: (2015)

sGC Activity and Regulation of Blood Flow in a Zebrafish Model System
por: Vishnolia, Krishan K., et al.
Publicado: (2021)

The Role of NO/sGC/cGMP/PKG Signaling Pathway in Regulation of Platelet Function
por: Gambaryan, Stepan
Publicado: (2022)

Soluble guanylyl cyclase: Molecular basis for ligand selectivity and action in vitro and in vivo
por: Wu, Gang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_7dqrgvsq575qdsb4m1nl4pfi1b