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Bioenergetic failure correlates with autophagy and apoptosis in rat liver following silver nanoparticle intraperitoneal administration

BACKGROUND: Deposition and accumulation of silver nanoparticles (Ag-nps) in the liver have been shown to induce hepatotoxicity in animal studies. The hepatotoxicity may include oxidative stress, abnormalities in energy metabolism, and cell death. Studies have indicated that autophagy is an intracell...

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Detalles Bibliográficos
Autores principales: Lee, Tzu-Ying, Liu, Maw-Shung, Huang, Li-Ju, Lue, Sheng-I, Lin, Lung-Chang, Kwan, Aij-Lie, Yang, Rei-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765627/
https://www.ncbi.nlm.nih.gov/pubmed/23958063
http://dx.doi.org/10.1186/1743-8977-10-40