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A new reporter mouse cytomegalovirus reveals maintained immediate-early gene expression but poor virus replication in cycling liver sinusoidal endothelial cells

BACKGROUND: The MCMV major immediate early promoter/enhancer (MIEP) is a bidirectional promoter that drives the expression of the three immediate early viral genes, namely ie1, ie2 and ie3. The regulation of their expression is intensively studied, but still incompletely understood. METHODS: We cons...

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Detalles Bibliográficos
Autores principales: Dag, Franziska, Weingärtner, Adrien, Butueva, Milada, Conte, Ianina, Holzki, Julia, May, Tobias, Adler, Barbara, Wirth, Dagmar, Cicin-Sain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765632/
https://www.ncbi.nlm.nih.gov/pubmed/23773211
http://dx.doi.org/10.1186/1743-422X-10-197

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