Abcb4 acts as multixenobiotic transporter and active barrier against chemical uptake in zebrafish (Danio rerio) embryos

BACKGROUND: In mammals, ABCB1 constitutes a cellular “first line of defense” against a wide array of chemicals and drugs conferring cellular multidrug or multixenobiotic resistance (MDR/MXR). We tested the hypothesis that an ABCB1 ortholog serves as protection for the sensitive developmental process...

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Detalles Bibliográficos
Autores principales: Fischer, Stephan, Klüver, Nils, Burkhardt-Medicke, Kathleen, Pietsch, Mirko, Schmidt, Anne-Marie, Wellner, Peggy, Schirmer, Kristin, Luckenbach, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765700/
https://www.ncbi.nlm.nih.gov/pubmed/23773777
http://dx.doi.org/10.1186/1741-7007-11-69

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