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Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes

BACKGROUND: Recent studies suggested that human/mammalian genomes are divided into large, discrete domains that are units of chromosome organization. CTCF, a CCCTC binding factor, has a diverse role in genome regulation including transcriptional regulation, chromosome-boundary insulation, DNA replic...

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Detalles Bibliográficos
Autores principales: Li, Yuanyuan, Huang, Weichun, Niu, Liang, Umbach, David M, Covo, Shay, Li, Leping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765723/
https://www.ncbi.nlm.nih.gov/pubmed/23945083
http://dx.doi.org/10.1186/1471-2164-14-553