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Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD), elevated in tumor cells, catalyzes the first reaction in the pentose-phosphate pathway. The regulation mechanism of G6PD and pathological change in human melanoma growth remains unknown. METHODS: HEM (human epidermal melanocyte) cells and human m...

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Detalles Bibliográficos
Autores principales:	Hu, Tao, Zhang, Chunhua, Tang, Qiongling, Su, Yanan, Li, Bo, Chen, Long, Zhang, Zheng, Cai, Tianchi, Zhu, Yuechun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765728/ https://www.ncbi.nlm.nih.gov/pubmed/23693134 http://dx.doi.org/10.1186/1471-2407-13-251

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