sTREM-1 as a Prognostic Marker of Postoperative Complications in Cardiac Surgery

Cell-activating receptor TREM-1 (triggering receptor expressed on myeloid cells 1) regulates congenital immune response and contributes to systemic inflammatory response syndrome (SIRS) development. It is able to multiply cytokine production while stimulated together with the main receptors of the c...

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Detalles Bibliográficos
Autores principales: Golovkin, A. S., Matveeva, V. G., Grigoriev, E. V., Shukevich, D. L., Bayrakova, Y. V., Barbarash, L. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Clinical Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765744/
https://www.ncbi.nlm.nih.gov/pubmed/24049646
http://dx.doi.org/10.5402/2012/382862
Descripción
Sumario:Cell-activating receptor TREM-1 (triggering receptor expressed on myeloid cells 1) regulates congenital immune response and contributes to systemic inflammatory response syndrome (SIRS) development. It is able to multiply cytokine production while stimulated together with the main receptors of the congenital immune system. The purpose of the paper is to study the potential use of soluble TREM-1 (sTREM-1) as a marker of intensive SIRS and a criterion for postoperative complications prediction following on-pump coronary artery bypass surgery (CABG). Results show that early postoperative sTREM-1 concentrations demonstrate their potential prognostic value regarding SIRS-associated complications.

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