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Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City

Objective. To describe the characteristics and interventions to control a large epidemiological Influenza A Outbreak. Methods. During the months of February to April 2006, a large outbreak of Influenza A was detected, which affected Health Care Workers and hospitalized patients in a large teaching H...

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Autores principales: Mejía, Carlos, Silvestre, Monica, Cazali, Iris, García, Judith, Sánchez, Ruth, García, Leticia, Castillo, Leticia, Escobar, Ingrid, Terraza, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765751/
https://www.ncbi.nlm.nih.gov/pubmed/24052881
http://dx.doi.org/10.5402/2012/638042
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author Mejía, Carlos
Silvestre, Monica
Cazali, Iris
García, Judith
Sánchez, Ruth
García, Leticia
Castillo, Leticia
Escobar, Ingrid
Terraza, Sandra
author_facet Mejía, Carlos
Silvestre, Monica
Cazali, Iris
García, Judith
Sánchez, Ruth
García, Leticia
Castillo, Leticia
Escobar, Ingrid
Terraza, Sandra
author_sort Mejía, Carlos
collection PubMed
description Objective. To describe the characteristics and interventions to control a large epidemiological Influenza A Outbreak. Methods. During the months of February to April 2006, a large outbreak of Influenza A was detected, which affected Health Care Workers and hospitalized patients in a large teaching Hospital in Guatemala City. Interventions to interrupt transmission were implemented and included barrier methods (N95 masks, respiratory isolation measures, etc.) and enhanced hand hygiene, vaccination of healthy Health Care Workers (HCW), restrictions for patient visits. Results. From February to April 2006, 59 hospitalized patients diagnosed with Influenza A. 19 AIDS patients (mortality: 71%) and 5/40 (12.5%) in other diseases: cancer (3), severe cardiac failure (1) and severe malnutrition (1). The attack rate at day 20 in doctors and medical students was 21% while in other HCW it was 10.5%. Within 3 weeks of the beginning of the plan, deaths were stopped and no more cases in HCW were detected after 3 additional weeks. Conclusion. A rapid, comprehensive plan for the control of nosocomial epidemic Influenza A outbreaks is essential to limit severe morbidity and mortality in hospitals who attend large immunocompromised populations, including AIDS patients. HCW regular vaccinations programs are mandatory.
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spelling pubmed-37657512013-09-19 Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City Mejía, Carlos Silvestre, Monica Cazali, Iris García, Judith Sánchez, Ruth García, Leticia Castillo, Leticia Escobar, Ingrid Terraza, Sandra ISRN AIDS Clinical Study Objective. To describe the characteristics and interventions to control a large epidemiological Influenza A Outbreak. Methods. During the months of February to April 2006, a large outbreak of Influenza A was detected, which affected Health Care Workers and hospitalized patients in a large teaching Hospital in Guatemala City. Interventions to interrupt transmission were implemented and included barrier methods (N95 masks, respiratory isolation measures, etc.) and enhanced hand hygiene, vaccination of healthy Health Care Workers (HCW), restrictions for patient visits. Results. From February to April 2006, 59 hospitalized patients diagnosed with Influenza A. 19 AIDS patients (mortality: 71%) and 5/40 (12.5%) in other diseases: cancer (3), severe cardiac failure (1) and severe malnutrition (1). The attack rate at day 20 in doctors and medical students was 21% while in other HCW it was 10.5%. Within 3 weeks of the beginning of the plan, deaths were stopped and no more cases in HCW were detected after 3 additional weeks. Conclusion. A rapid, comprehensive plan for the control of nosocomial epidemic Influenza A outbreaks is essential to limit severe morbidity and mortality in hospitals who attend large immunocompromised populations, including AIDS patients. HCW regular vaccinations programs are mandatory. International Scholarly Research Network 2012-08-01 /pmc/articles/PMC3765751/ /pubmed/24052881 http://dx.doi.org/10.5402/2012/638042 Text en Copyright © 2012 Carlos Mejía et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Mejía, Carlos
Silvestre, Monica
Cazali, Iris
García, Judith
Sánchez, Ruth
García, Leticia
Castillo, Leticia
Escobar, Ingrid
Terraza, Sandra
Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City
title Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City
title_full Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City
title_fullStr Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City
title_full_unstemmed Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City
title_short Large Epidemiological Influenza A Outbreak in a Teaching Hospital from Guatemala City
title_sort large epidemiological influenza a outbreak in a teaching hospital from guatemala city
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765751/
https://www.ncbi.nlm.nih.gov/pubmed/24052881
http://dx.doi.org/10.5402/2012/638042
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