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DNA methylation within the I.4 promoter region correlates with CYPl19A1 gene expression in human ex vivo mature omental and subcutaneous adipocytes

BACKGROUND: DNA methylation at specific CpG sites within gene promoter regions is known to regulate transcriptional activity in vitro. In human adipose tissue, basal transcription of the aromatase (CYP19A1) gene is driven primarily by the I.4 promoter however the role of DNA methylation in regulatin...

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Detalles Bibliográficos
Autores principales:	Lewis, Joshua R, McNab, Tegan J, Liew, Lawrence J, Tan, Jeremy, Hudson, Phillip, Wang, Jenny Z, Prince, Richard L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765767/ https://www.ncbi.nlm.nih.gov/pubmed/24128150 http://dx.doi.org/10.1186/1471-2350-14-87

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