Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst

Synthesis of 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidin-2(1H)-thione derivatives from aldehydes, 1,3-dicarbonyl derivatives and urea or thiourea using granite and quartz as new, natural and reusable catalysts. Some of the 3,4-dihydropyrimidin-2(1H)-thione derivatives were used to prepar...

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Detalles Bibliográficos
Autores principales: Elmaghraby, A. M., Mousa, I. A., Harb, A. A., Mahgoub, M. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765801/
https://www.ncbi.nlm.nih.gov/pubmed/24052868
http://dx.doi.org/10.1155/2013/706437
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author Elmaghraby, A. M.
Mousa, I. A.
Harb, A. A.
Mahgoub, M. Y.
author_facet Elmaghraby, A. M.
Mousa, I. A.
Harb, A. A.
Mahgoub, M. Y.
author_sort Elmaghraby, A. M.
collection PubMed
description Synthesis of 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidin-2(1H)-thione derivatives from aldehydes, 1,3-dicarbonyl derivatives and urea or thiourea using granite and quartz as new, natural and reusable catalysts. Some of the 3,4-dihydropyrimidin-2(1H)-thione derivatives were used to prepare new heterocyclic compounds. The antimicrobial activity of selected examples of the synthesized compounds was tested and showed moderate activity.
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spelling pubmed-37658012013-09-19 Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst Elmaghraby, A. M. Mousa, I. A. Harb, A. A. Mahgoub, M. Y. ISRN Org Chem Research Article Synthesis of 3,4-dihydropyrimidin-2(1H)-one and 3,4-dihydropyrimidin-2(1H)-thione derivatives from aldehydes, 1,3-dicarbonyl derivatives and urea or thiourea using granite and quartz as new, natural and reusable catalysts. Some of the 3,4-dihydropyrimidin-2(1H)-thione derivatives were used to prepare new heterocyclic compounds. The antimicrobial activity of selected examples of the synthesized compounds was tested and showed moderate activity. Hindawi Publishing Corporation 2013-08-18 /pmc/articles/PMC3765801/ /pubmed/24052868 http://dx.doi.org/10.1155/2013/706437 Text en Copyright © 2013 A. M. Elmaghraby et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Elmaghraby, A. M.
Mousa, I. A.
Harb, A. A.
Mahgoub, M. Y.
Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst
title Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst
title_full Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst
title_fullStr Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst
title_full_unstemmed Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst
title_short Three Component Reaction: An Efficient Synthesis and Reactions of 3,4-Dihydropyrimidin-2(1H)-Ones and Thiones Using New Natural Catalyst
title_sort three component reaction: an efficient synthesis and reactions of 3,4-dihydropyrimidin-2(1h)-ones and thiones using new natural catalyst
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765801/
https://www.ncbi.nlm.nih.gov/pubmed/24052868
http://dx.doi.org/10.1155/2013/706437
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