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The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase
BACKGROUND: The yeast Saccharomyces cerevisiae can be a useful model for studying cellular mechanisms related to sterol synthesis in humans due to the high similarity of the mevalonate pathway between these organisms. This metabolic pathway plays a key role in multiple cellular processes by synthesi...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765880/ https://www.ncbi.nlm.nih.gov/pubmed/24128347 http://dx.doi.org/10.1186/1472-6750-13-68 |