ITGB5 and AGFG1 variants are associated with severity of airway responsiveness

BACKGROUND: Airway hyperresponsiveness (AHR), a primary characteristic of asthma, involves increased airway smooth muscle contractility in response to certain exposures. We sought to determine whether common genetic variants were associated with AHR severity. METHODS: A genome-wide association study...

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Detalles Bibliográficos
Autores principales: Himes, Blanca E, Qiu, Weiliang, Klanderman, Barbara, Ziniti, John, Senter-Sylvia, Jody, Szefler, Stanley J, Lemanske, Jr, Robert F, Zeiger, Robert S, Strunk, Robert C, Martinez, Fernando D, Boushey, Homer, Chinchilli, Vernon M, Israel, Elliot, Mauger, David, Koppelman, Gerard H, Nieuwenhuis, Maartje AE, Postma, Dirkje S, Vonk, Judith M, Rafaels, Nicholas, Hansel, Nadia N, Barnes, Kathleen, Raby, Benjamin, Tantisira, Kelan G, Weiss, Scott T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765944/
https://www.ncbi.nlm.nih.gov/pubmed/23984888
http://dx.doi.org/10.1186/1471-2350-14-86

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