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FMNL2 Drives Actin-Based Protrusion and Migration Downstream of Cdc42

Cell migration entails protrusion of lamellipodia, densely packed networks of actin filaments at the cell front. Filaments are generated by nucleation, likely mediated by Arp2/3 complex and its activator Scar/WAVE [1]. It is unclear whether formins contribute to lamellipodial actin filament nucleati...

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Detalles Bibliográficos
Autores principales:	Block, Jennifer, Breitsprecher, Dennis, Kühn, Sonja, Winterhoff, Moritz, Kage, Frieda, Geffers, Robert, Duwe, Patrick, Rohn, Jennifer L., Baum, Buzz, Brakebusch, Cord, Geyer, Matthias, Stradal, Theresia E.B., Faix, Jan, Rottner, Klemens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765947/ https://www.ncbi.nlm.nih.gov/pubmed/22608513 http://dx.doi.org/10.1016/j.cub.2012.03.064

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