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Interactions between HIV-1 Vif and human ElonginB-ElonginC are important for CBF-β binding to Vif

BACKGROUND: The HIV-1 accessory factor Vif is necessary for efficient viral infection in non-permissive cells. Vif antagonizes the antiviral activity of human cytidine deaminase APOBEC3 proteins that confer the non-permissive phenotype by tethering them (APOBEC3DE/3F/3G) to the Vif-CBF-β-ElonginB-El...

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Detalles Bibliográficos
Autores principales: Wang, Xiaodan, Wang, Xiaoying, Zhang, Haihong, Lv, Mingyu, Zuo, Tao, Wu, Hui, Wang, Jiawen, Liu, Donglai, Wang, Chu, Zhang, Jingyao, Li, Xu, Wu, Jiaxin, Yu, Bin, Kong, Wei, Yu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765967/
https://www.ncbi.nlm.nih.gov/pubmed/23988114
http://dx.doi.org/10.1186/1742-4690-10-94