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Cardiac angiogenesis directed by stable Hypoxia Inducible Factor-1

BACKGROUND: The heterodimeric, oxygen-sensitive transcription factor Hypoxia Inducible Factor-1 (HIF-1) orchestrates angiogenesis and plays a key role in the response to ischemia and the growth of cancers. METHODS: We developed a transgenic mouse line in which expression of an oxygen-stable HIF-1α c...

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Detalles Bibliográficos
Autores principales:	Walton, Chad B, Ecker, Jennifer, Anderson, Cynthia D, Outten, Joel T, Allison, Randall Z, Shohet, Ralph V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766207/ https://www.ncbi.nlm.nih.gov/pubmed/23987100 http://dx.doi.org/10.1186/2045-824X-5-15

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