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Amyotrophic lateral sclerosis-linked FUS/TLS alters stress granule assembly and dynamics

BACKGROUND: Amyotrophic lateral sclerosis (ALS)-linked fused in sarcoma/translocated in liposarcoma (FUS/TLS or FUS) is concentrated within cytoplasmic stress granules under conditions of induced stress. Since only the mutants, but not the endogenous wild-type FUS, are associated with stress granule...

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Detalles Bibliográficos
Autores principales:	Baron, Desiree M, Kaushansky, Laura J, Ward, Catherine L, Sama, Reddy Ranjith K, Chian, Ru-Ju, Boggio, Kristin J, Quaresma, Alexandre J C, Nickerson, Jeffrey A, Bosco, Daryl A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766239/ https://www.ncbi.nlm.nih.gov/pubmed/24090136 http://dx.doi.org/10.1186/1750-1326-8-30

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