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Methylation impact analysis of erythropoietin (EPO) Gene to hypoxia inducible factor-1α (HIF-1α) activity

Erythropoietin (EPO) is a glycoprotein hormone that play a role as key regulator in the production of red blood cells. The promoter region of EPO is methylated in normoxic (non-hypoxia) condition, but not in hypoxic condition. Methylation of the EPO enhancer region decline the transcription activity...

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Detalles Bibliográficos
Autores principales:	Dewi, Firli Rahmah Primula, Fatchiyah, Fatchiyah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2013
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766311/ https://www.ncbi.nlm.nih.gov/pubmed/24023421 http://dx.doi.org/10.6026/97320630009782

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