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The utility of ionotropic glutamate receptor antagonists in the treatment of nociception induced by epidural glutamate infusion in rats
BACKGROUND: The authors have previously demonstrated that human herniated disc material contains high concentrations of free glutamate. In an experimental model, elevated epidural glutamate concentrations in the lumbar spine can cause a focal hyperesthetic state. METHODS: Rats underwent epidural glu...
Autores principales: | Osgood, Doreen P., Harrington, William F., Kenney, Elizabeth V., Harrington, J. Frederick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3766326/ https://www.ncbi.nlm.nih.gov/pubmed/24032081 http://dx.doi.org/10.4103/2152-7806.116791 |
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